ANA Highlights

• Are you looking for a digestible way to learn next-level statistical concepts? 
• Have you forgotten critical Epidemiology terms from Medical School?
• Are you an academic neuroscientist who is trying to understand the best techniques to apply to your research?

The ANA Highlight's Statistical Snapshots series is an excellent way to meet your goals. In this series of seven modules, ranging from 10-22 minutes, you will find a high-yield overview of critical statistical concepts that go beyond interpretation of p-values to provide a foundation by which to conduct research, regardless of level or training.

Did you enjoy this series? Is there an area in which you would like to dig deeper? Email the ANA at jhurley@myana.org and let us know what you thought!

This program is comprised of the following bite-size videos. 

• Sensitivity & Specificity (~12 minutes)
• Essential Study Design and Statistical Concepts for the Clinician Scientist (~22 minutes)
• Adaptive Designs (~18 minutes)
• Biases, Confounders, and Mediators (~17 minutes)
• Linear Regression (~10 minutes)
• The Odds Ratio (~18 minutes)
• Clinical Trial Design: The Statistician's Perspective (~20 minutes) 

• Interviewer/Producer: Rohit Das, MD, MPH, UT Southwestern
• Interviewer/Producer: Michelle C. Johansen, MD, PhD , Johns Hopkins University

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Functional Movement Disorders (FMD) are as prevalent as Multiple Sclerosis (MS) yet remain understudied. Like MS, FMD predominantly affect women, has historically been referred to as “hysteria” or “conversion disorder” and remains a highly stigmatized condition. In this 43 minute video, Dr. LaFaver walks us through history, etiology, diagnostic considerations, and treatment options for FMD. Her call to ANA researchers is to join her in helping these underserved and often highly disabled patients through clinical and translational research efforts and establishing specialized treatment centers throughout the US. Connect with Dr. LaFaver on Twitter: @LaFaverMD

• Interviewer/Producer: Kathrin LaFaver, MD, Associate Professor of Neurology, Northwestern University Feinberg School of Medicine

The planners and faculty for this activity have no relevant relationships to disclose. When applicable, all relevant financial relationships have been mitigated.

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In this 19-minute video, Dr. Jee Bang provides an overview of the current state of research and therapy for Huntington Disease. 

• Interviewer/Producer: Dr Jee Bang, MD, MPH, Assistant Professor of Neurology at the Johns Hopkins University School of Medicine & Clinical Director, Johns Hopkins Huntington Disease Center of Excellence

The planners and faculty for this activity have no relevant relationships to disclose, unless listed below:

• Dr. Bang disclosed contracted research from Roche and uniQure

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In this 12-minute video, Dr. Basil Darras, Professor of Neurology at Boston Children’s Hospital and Harvard Medical School, introduces the learner to spinal muscular atrophy (SMA), the number one genetic cause of death in infants. SMA is a genetic disorder characterized by degeneration and loss of motor neurons in the anterior horns of the spinal cord and brain stem of children and adults, with limited involvement of peripheral organs in severely affected patients. What are the extra-neuronal phenotypes of SMA in humans and animal models? Part 1 of 2. 

• The article referenced during the videos may be found here: https://www.pedneur.com/article/S0887-8994(20)30027-8/abstract 

• Interviewer/Producer: Dr Basil Darras, Professor of Neurology, Director, Neuromuscular Center and SMA Program, Boston Children's Hospital, Harvard Medical School

The planners and faculty for this activity have no relevant relationships to disclose, unless listed below:

• Dr. Darras provided disclosures at the start of his presentation

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In part 2 of this series, Dr. Crystal Yeo, Assistant Professor at LKC School of Medicine, Associated Staff at Boston Children’s Hospital, joint Medical Director at EDDC and Group Leader at IMCB, continues on to review the changing therapeutic landscape for spinal muscular atrophy (SMA), the extra-neuronal expression of survival motor neuron (SMN) protein, and motor neuron cell-non-autonomous rescue in animal models. What are the clinical implications for patients treated with SMN protein augmenting interventions? In the era of innovative therapies, why is it important for physicians, scientists and others to be aware of the potential emergence of extra-neuronal phenotypes in treated SMA patients?  Part 2 of 2. 

• Interviewer/Producer: Dr Crystal Yeo, Assistant Professor at LKC School of Medicine, Associated Staff at Boston Children’s Hospital, joint Medical Director at EDDC and Group Leader at IMCB

The planners and faculty for this activity have no relevant relationships to disclose.

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During this 36-minute video, Dr. Thanh Nguyen takes us through the origin of COVID-19 and its impact on stroke care - both for patients and clinicians. Note: Dr. Nguyen obtained permission to use the images used in this presentation and offered disclosures at the start of the presentation. 

• Interviewer/Producer: Dr Thanh Nguyen, Professor, Neurology, Neurosurgery, Radiology, Director, Neuroendovascular Service, Boston University School of Medicine, Boston Medical Center

The planners and faculty for this activity have no relevant relationships to disclose.

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In this 38 minute video, we hear insights from Justin C. McArthur, MBBS, MPH, President, American Neurological Association, and John W. Griffin Professor of Neurology and Director, Department of Neurology at Johns Hopkins Medicine on how we might approach the future amid COVID-19.

• Interviewer/Producer: Justin McArthur, MBBS, MPH, President, American Neurological Association
• Interviewer/Producer: John Griffin, Professor of Neurology and Director, Department of Neurology at Johns Hopkins Medicine

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In this 19-minute presentation, Dr. Deanna Saylor Assistant Professor of Neurology, Director, Hopkins Global Neurology Program at the Johns Hopkins University School of Medicine and currently on assignment in Zambia, talks us through how the current pandemic environment elevates the importance of partnering globally to learn from each other, acting globally by taking assignments in areas in most need, and thinking globally by considering where global perspectives may improve research. All, so we may together, tackle neurologic conditions that continue to cause disability and mortality in patients all over the world. CME value: .5 AMA PRA Category 1 CreditsTM

• Interviewer/Producer: Dr Deanna Saylor, Assistant Professor of Neurology, Director, Hopkins Global Neurology Program at the Johns Hopkins University School of Medicine

The planners and faculty for this activity have no relevant relationships to disclose.

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