Nobel Laureate Dr. Gregg Semenza to Speak during ANA2021
Leaders in the Field Explore Hypoxic/Anoxic Injury in the CNS and Novel Therapies
Date/Time: Tuesday, October 19, 2021 - 2:00 PM – 4:00 PM ET
Chair: Jennifer Frontera, MD, FANA, New York University
Co-Chair: Marion Buckwalter, MD, PhD, Stanford School of Medicine
Throughout this year’s virtual meeting, ANA2021 will feature groundbreaking research that leads to new developments in therapeutics in acquired and inherited neurological diseases. In this session, Nobel Prize-winning scientist Gregg Semenza, MD, PhD will introduce the audience to HIF hypoxia-inducible factors that play a role in gene regulation in variable oxygen environments.
HIF is instrumental in regulating the transcription of genes involved in adaptive responses to hypoxia, such as glycolysis, erythropoiesis, angiogenesis, and vascular remodeling. There may be therapeutic roles for HIF modulation in cancer therapy, stroke treatment, and management of hypoxic-ischemic encephalopathy in neonates. This session will also touch on ferroptosis and neuronal death as well as post-stroke recovery strategies including novel therapies such as transcortical magnetic stimulation.
Harnessing Hypoxic Adaptation to Interdict Ferroptosis and Treat Neurological Diseases
SPEAKER: Rajiv Ratan, MD, PhD, Cornell University
Hypoxia-Inducible Factors in Physiology and Medicine
SPEAKER: Gregg Semenza, MD, PhD, Johns Hopkins University School of Medicine
Precision Therapy for Neonatal HI: Role of HIF and Metabolomics
SPEAKER: Donna Ferriero, MD, MS, University of California, San Francisco
Transcranial Magnetic Stimulation (TMS) and Post-Stroke Recovery
SPEAKER: Roy Hamilton, MD, MS, University of Pennsylvania