Researchers at ANA2019 Report New Insights Into HIV-Related Neurocognitive Disorders

The use of antiretroviral therapy (ART) has allowed patients with HIV to have a life expectancy that approaches the lifespan of those without HIV. Despite this progress, however, HIV-associated neurocognitive disorders remain prevalent, and range from mild problems with memory, language, and reasoning to more severe HIV-associated dementia.

Frailty has also emerged as an age-related comorbidity in patients with HIV, and at the recent American Neurological Association 2019 meeting, held in St. Louis, Missouri, researchers reported on efforts to use deep learning algorithms of cerebral blood flow to classify both cognitive impairment and frailty in patients living with HIV, and said that they were able to predict brain regions for each domain, and to identify brain regions that overlap between cognitive impairment and frailty. 

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